AirHint found the following cheapest return flights from Cartagena (CTG) to Madrid (MAD) in October 2025 (see full year).

Return flights

29 Oct - 12 Nov	SWISS
29 Oct - 18 Nov	SWISS
13 Oct - 10 Nov	KLM
20 Oct - 10 Nov	KLM
19 Oct - 04 Nov	KLM
23 Oct - 17 Nov	KLM
08 Oct - 04 Nov	KLM
27 Oct - 19 Nov	KLM
21 Oct - 28 Oct	KLM
19 Oct - 23 Nov	KLM
28 Oct - 19 Nov	KLM
02 Oct - 16 Oct	Spirit Airlines
08 Oct - 28 Oct	KLM
17 Oct - 24 Oct	JetSmart
17 Oct - 23 Oct	Spirit Airlines
19 Oct - 26 Oct	Arajet
11 Oct - 23 Oct	Spirit Airlines
02 Oct - 23 Oct	Spirit Airlines
07 Oct - 16 Oct	Avianca
12 Oct - 19 Oct	Arajet

Also check the deals for one-way flights from Cartagena to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cartagena to Madrid in October from $680

Return flights