Cheapest one-way flights from Houston to Panama City in December from $198

AirHint found the following cheapest one-way flights from Houston (IAH) to Panama City (PTY) in December 2025 (see full year).

One-Way flights

31 Dec Frontier Airlines
30 Dec Spirit Airlines
28 Dec Spirit Airlines
29 Dec Spirit Airlines
26 Dec Frontier Airlines
25 Dec Spirit Airlines
24 Dec Frontier Airlines
27 Dec Frontier Airlines
16 Dec Avianca
22 Dec Frontier Airlines

Also check the deals for return flights from Houston to Panama City in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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