AirHint found the following cheapest one-way flights from Istanbul (IST) to Madrid (MAD) in April 2026 (see full year).
One-Way flights
| 06 Apr | Aegean Airlines | ||
| 11 Apr | Aegean Airlines | ||
| 04 Apr | Wizz Air UK | ||
| 04 Apr | Turkish Airlines | direct | |
| 06 Apr | Turkish Airlines | direct | |
| 11 Apr | Turkish Airlines | direct |
Also check the deals for return flights from Istanbul to Madrid in April.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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