Cheapest return flights from Istanbul to Madrid in April from $242

AirHint found the following cheapest return flights from Istanbul (IST) to Madrid (MAD) in April 2026 (see full year).

Return flights

23 Apr - 26 Apr Aegean Airlines
08 Apr - 22 Apr Aegean Airlines
01 Apr - 09 Apr Aegean Airlines
25 Apr - 02 May Aegean Airlines
28 Apr - 21 May Lufthansa
11 Apr - 22 Apr Wizz Air UK
23 Apr - 26 Apr Air Europa direct
28 Apr - 21 May Air Europa direct
25 Apr - 02 May Air Europa direct
01 Apr - 09 Apr Turkish Airlines direct
11 Apr - 22 Apr Turkish Airlines direct
08 Apr - 22 Apr Turkish Airlines direct

Also check the deals for one-way flights from Istanbul to Madrid in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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