AirHint found the following cheapest one-way flights from Istanbul (IST) to Madrid (MAD) in May 2026 (see full year).
One-Way flights
| 23 May | Aegean Airlines | ||
| 20 May | Aegean Airlines | ||
| 08 May | Aegean Airlines | ||
| 08 May | Air Europa | direct | |
| 23 May | Air Europa | direct | |
| 20 May | Air Europa | direct |
Also check the deals for return flights from Istanbul to Madrid in May.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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