Cheapest one-way flights from Istanbul to San Francisco in December from $443

AirHint found the following cheapest one-way flights from Istanbul (IST) to San Francisco (SFO) in December 2025 (see full year).

One-Way flights

06 Dec Wizz Air UK
12 Dec Wizz Air UK
08 Dec Pegasus Airlines
02 Dec Pegasus Airlines
03 Dec Pegasus Airlines
01 Dec Pegasus Airlines
09 Dec Turkish Airlines direct
10 Dec Turkish Airlines direct
03 Dec Turkish Airlines direct
06 Dec Turkish Airlines direct

Also check the deals for return flights from Istanbul to San Francisco in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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