AirHint found the following cheapest one-way flights from Istanbul (IST) to San Francisco (SFO) in April 2026 (see full year).
One-Way flights
| 20 Apr | British Airways | ||
| 24 Apr | British Airways | ||
| 09 Apr | British Airways | ||
| 09 Apr | Turkish Airlines | direct | |
| 20 Apr | Turkish Airlines | direct | |
| 24 Apr | Turkish Airlines | direct |
Also check the deals for return flights from Istanbul to San Francisco in April.
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