Cheapest return flights from Istanbul to San Francisco in April from $512

AirHint found the following cheapest return flights from Istanbul (IST) to San Francisco (SFO) in April 2026 (see full year).

Return flights

08 Apr - 13 Apr KLM
04 Apr - 13 Apr Air France
18 Apr - 02 May KLM
01 Apr - 10 Apr Lufthansa
01 Apr - 10 Apr Turkish Airlines direct
04 Apr - 13 Apr Turkish Airlines direct
08 Apr - 13 Apr Turkish Airlines direct
18 Apr - 02 May Turkish Airlines direct

Also check the deals for one-way flights from Istanbul to San Francisco in April.

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