Cheapest one-way flights from Los Angeles to Santiago in October from $311

AirHint found the following cheapest one-way flights from Los Angeles (LAX) to Santiago (SCL) in October 2025 (see full year).

One-Way flights

13 Oct Frontier Airlines
24 Oct Spirit Airlines
17 Oct Spirit Airlines
30 Oct Frontier Airlines
31 Oct Frontier Airlines
21 Oct Spirit Airlines
16 Oct Frontier Airlines
11 Oct Frontier Airlines
13 Oct LATAM Airlines Group direct
31 Oct LATAM Airlines Group direct

Also check the deals for return flights from Los Angeles to Santiago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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