Cheapest return flights from Los Angeles to Santiago in October from $648

AirHint found the following cheapest return flights from Los Angeles (LAX) to Santiago (SCL) in October 2025 (see full year).

Return flights

06 Oct - 27 Oct Spirit Airlines
07 Oct - 28 Oct Avianca
30 Oct - 09 Nov Avianca
27 Oct - 06 Nov Avianca
31 Oct - 10 Nov Spirit Airlines
28 Oct - 02 Nov Copa
01 Oct - 06 Oct Spirit Airlines
12 Oct - 20 Oct Copa
24 Oct - 01 Nov LATAM Airlines Group
12 Oct - 20 Oct Delta direct

Also check the deals for one-way flights from Los Angeles to Santiago in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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