Cheapest one-way flights from Los Angeles to Santiago in September from 256€

AirHint found the following cheapest one-way flights from Los Angeles (LAX) to Santiago (SCL) in September 2025 (see full year).

One-Way flights

27 Sep Spirit Airlines
06 Sep Spirit Airlines
02 Sep Spirit Airlines
14 Sep Frontier Airlines
04 Sep Frontier Airlines
03 Sep Spirit Airlines
21 Sep Spirit Airlines
18 Sep LATAM Airlines Group
20 Sep Spirit Airlines
30 Sep LATAM Airlines Group

Also check the deals for return flights from Los Angeles to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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