Cheapest one-way flights from Lisbon to Santiago in December from $577

AirHint found the following cheapest one-way flights from Lisbon (LIS) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

03 Dec Azul Airlines
02 Dec Azul Airlines
05 Dec Azul Airlines
12 Dec Azul Airlines
31 Dec LATAM Airlines Group
10 Dec LATAM Airlines Group
15 Dec easyJet
26 Dec Iberia
11 Dec Royal Air Maroc
14 Dec Air Europa

Also check the deals for return flights from Lisbon to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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