Cheapest one-way flights from Lisbon to Sao Tome in December from $363

AirHint found the following cheapest one-way flights from Lisbon (LIS) to Sao Tome (TMS) in December 2025 (see full year).

One-Way flights

02 Dec TAAG Angola Airlines
03 Dec TAP
04 Dec TAAG Angola Airlines
31 Dec TAP
06 Dec TAP direct
07 Dec TAAG Angola Airlines
12 Dec Royal Air Maroc
15 Dec Royal Air Maroc
13 Dec TAP direct
14 Dec TAAG Angola Airlines

Also check the deals for return flights from Lisbon to Sao Tome in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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