Cheapest one-way flights from Madrid to Istanbul in April from $205
AirHint found the following cheapest one-way flights from Madrid (MAD) to Istanbul (IST) in April 2026 (see full year).
One-Way flights
| 02 Apr | TAROM | ||
| 04 Apr | TAROM | ||
| 05 Apr | TAROM | ||
| 16 Apr | Lufthansa | ||
| 16 Apr | Air Europa | direct | |
| 05 Apr | Turkish Airlines | direct | |
| 02 Apr | Turkish Airlines | direct | |
| 04 Apr | Turkish Airlines | direct |
Also check the deals for return flights from Madrid to Istanbul in April.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
