Cheapest one-way flights from Madrid to Prague in September from $61

AirHint found the following cheapest one-way flights from Madrid (MAD) to Prague (PRG) in September 2026 (see full year).

One-Way flights

07 Sep Ryanair direct
22 Sep Ryanair direct
17 Sep Ryanair direct
24 Sep Ryanair direct
06 Sep Ryanair direct
15 Sep Ryanair direct
14 Sep Ryanair direct
03 Sep Ryanair
03 Sep Ryanair direct
25 Sep Wizz Air UK

Also check the deals for return flights from Madrid to Prague in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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