Cheapest return flights from Madrid to Prague in September from $111

AirHint found the following cheapest return flights from Madrid (MAD) to Prague (PRG) in September 2025 (see full year).

Return flights

30 Sep - 21 Oct Ryanair direct
30 Sep - 01 Oct Ryanair direct
25 Sep - 01 Oct Ryanair direct
30 Sep - 14 Oct Ryanair direct
30 Sep - 15 Oct Ryanair direct
30 Sep - 08 Oct Ryanair direct
25 Sep - 14 Oct Ryanair direct
25 Sep - 15 Oct Ryanair direct
25 Sep - 08 Oct Ryanair direct
30 Sep - 07 Oct Ryanair direct
09 Sep - 17 Sep Ryanair direct
06 Sep - 17 Sep Ryanair direct
25 Sep - 30 Sep Ryanair
02 Sep - 17 Sep Ryanair direct
24 Sep - 28 Sep Wizz Air Malta
09 Sep - 23 Sep Ryanair direct
06 Sep - 23 Sep Ryanair direct
10 Sep - 23 Sep Ryanair
22 Sep - 24 Sep Ryanair
09 Sep - 25 Sep Ryanair direct

Also check the deals for one-way flights from Madrid to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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