Cheapest one-way flights from Madrid to Santiago in October from $548

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCL) in October 2026 (see full year).

One-Way flights

13 Oct Ryanair
01 Oct Ryanair
21 Oct Transavia France
31 Oct Iberojet
02 Oct Wizz Air Malta
29 Oct Iberia
11 Oct Iberia
12 Oct Iberia
29 Oct LATAM Airlines Group direct
30 Oct LATAM Airlines Group direct

Also check the deals for return flights from Madrid to Santiago in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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