AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCL) in September 2026 (see full year).
One-Way flights
| 19 Sep | Iberojet | ||
| 03 Sep | LATAM Airlines Group | direct | |
| 19 Sep | LATAM Airlines Group | direct | |
| 22 Sep | Delta | ||
| 13 Sep | Delta | ||
| 12 Sep | Delta | ||
| 30 Sep | Iberia | direct |
Also check the deals for return flights from Madrid to Santiago in September.
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