Cheapest return flights from Madrid to Santiago in September from $798

Best time to book flights for Madrid (MAD) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in September 2025 (see full year).

Return flights

14 Sep - 26 Sep Delta
09 Sep - 26 Sep Delta
11 Sep - 26 Sep Delta
10 Sep - 26 Sep Delta
03 Sep - 26 Sep Delta
16 Sep - 26 Sep Delta
17 Sep - 26 Sep Delta
04 Sep - 21 Sep Delta
11 Sep - 21 Sep Delta
08 Sep - 21 Sep Delta
08 Sep - 05 Oct Delta
17 Sep - 01 Oct Delta
17 Sep - 31 Oct Iberia
16 Sep - 07 Oct Delta
17 Sep - 22 Oct Delta
16 Sep - 02 Oct Iberia
17 Sep - 10 Oct Iberia
15 Sep - 15 Oct Air Europa
12 Sep - 03 Oct Iberia
12 Sep - 02 Oct Iberia

Also check the deals for one-way flights from Madrid to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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