Cheapest one-way flights from Madrid to Santa Cruz in December from $598
AirHint found the following cheapest one-way flights from Madrid (MAD) to Santa Cruz (VVI) in December 2025 (see full year).
One-Way flights
Also check the deals for return flights from Madrid to Santa Cruz in December.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
