Cheapest one-way flights from Rio Negro to Madrid in December from $441

AirHint found the following cheapest one-way flights from Rio Negro (MDE) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

04 Dec Spirit Airlines
03 Dec Spirit Airlines
05 Dec Spirit Airlines
06 Dec Spirit Airlines
10 Dec Spirit Airlines
09 Dec Spirit Airlines
02 Dec JetSmart
13 Dec Avianca
07 Dec Wingo
14 Dec LATAM Airlines Group

Also check the deals for return flights from Rio Negro to Madrid in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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