Cheapest one-way flights from Rio Negro to Madrid in December from $371

AirHint found the following cheapest one-way flights from Rio Negro (MDE) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

05 Dec Air Europa direct
02 Dec Air Europa direct
03 Dec Air Europa direct
07 Dec Air Europa direct
01 Dec Air Europa direct
04 Dec Air Europa direct
06 Dec Air Europa direct
08 Dec Air Europa direct
24 Dec Air Europa direct
11 Dec Spirit Airlines

Also check the deals for return flights from Rio Negro to Madrid in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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