AirHint found the following cheapest return flights from Rio Negro (MDE) to Madrid (MAD) in December 2025 (see full year).

Return flights

18 Dec - 15 Jan	JetSmart
19 Dec - 07 Jan	Avianca
30 Dec - 19 Jan	Air Europa	direct
19 Dec - 10 Jan	Avianca
04 Dec - 15 Jan	Air Europa	direct
07 Dec - 17 Jan	Air Europa	direct
25 Dec - 05 Jan	Air Europa	direct
20 Dec - 11 Jan	LATAM Airlines Group
22 Dec - 02 Jan	JetSmart
27 Dec - 19 Jan	Air Europa	direct
03 Dec - 30 Dec	Air Europa	direct
15 Dec - 29 Dec	Air Europa	direct
17 Dec - 30 Dec	Air Europa	direct
15 Dec - 28 Dec	JetSmart
10 Dec - 15 Dec	JetSmart
08 Dec - 13 Dec	JetSmart
15 Dec - 28 Dec	Air Europa	direct
08 Dec - 22 Dec	JetSmart
19 Dec - 28 Dec	Air Europa	direct
01 Dec - 20 Dec	Avianca

Also check the deals for one-way flights from Rio Negro to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid

Cheapest return flights from Rio Negro to Madrid in December from $833

Return flights