AirHint found the following cheapest return flights from Rio Negro (MDE) to Madrid (MAD) in December 2025 (see full year).

Return flights

27 Dec - 25 Jan	Wingo
31 Dec - 28 Jan	Spirit Airlines
30 Dec - 31 Jan	jetBlue
29 Dec - 29 Jan	Wingo
31 Dec - 31 Jan	Wingo
29 Dec - 23 Jan	Wingo
29 Dec - 30 Jan	Wingo
24 Dec - 24 Jan	Copa
28 Dec - 28 Jan	Spirit Airlines
28 Dec - 10 Jan	Avianca
24 Dec - 28 Dec	Copa
25 Dec - 28 Dec	Spirit Airlines
26 Dec - 29 Dec	Satena
27 Dec - 29 Dec	Avianca
24 Dec - 28 Dec	Avianca	direct
26 Dec - 29 Dec	Avianca	direct
24 Dec - 31 Dec	Avianca	direct
25 Dec - 28 Dec	Air Europa	direct

Also check the deals for one-way flights from Rio Negro to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Madrid in December from $942

Return flights