Cheapest one-way flights from Melbourne to Santiago in December from $1261

AirHint found the following cheapest one-way flights from Melbourne (MEL) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

28 Dec LATAM Airlines Group direct
04 Dec Qantas direct
09 Dec Qantas direct
08 Dec Qantas direct
05 Dec Qantas direct
07 Dec Qantas direct
25 Dec LATAM Airlines Group direct
15 Dec Air New Zealand
26 Dec LATAM Airlines Group direct
11 Dec Qantas

Also check the deals for return flights from Melbourne to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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