AirHint found the following cheapest return flights from Melbourne (MEL) to Santiago (SCL) in December 2025 (see full year).

Return flights

10 Dec - 26 Jan	Cathay Pacific
01 Dec - 11 Dec	Qantas	direct
31 Dec - 31 Jan	Turkish Airlines
31 Dec - 31 Jan	LATAM Airlines Group	direct
29 Dec - 31 Jan	LATAM Airlines Group	direct
13 Dec - 31 Dec	Qantas
31 Dec - 20 Jan	LATAM Airlines Group
02 Dec - 06 Jan	Qantas
31 Dec - 20 Jan	Qantas	direct
30 Dec - 30 Jan	Qantas	direct
04 Dec - 09 Jan	Qantas
01 Dec - 09 Jan	Qantas
13 Dec - 31 Dec	LATAM Airlines Group	direct

Also check the deals for one-way flights from Melbourne to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Melbourne to Santiago in December from $1916

Return flights