AirHint found the following cheapest return flights from Melbourne (MEL) to Santiago (SCL) in December 2025 (see full year).

Return flights

29 Dec - 09 Jan	Qantas
29 Dec - 10 Jan	Qantas
31 Dec - 03 Jan	Qantas
28 Dec - 09 Jan	Qantas
28 Dec - 10 Jan	Qantas
25 Dec - 22 Jan	Qantas	direct
17 Dec - 01 Jan	Qantas
26 Dec - 10 Jan	Qantas
26 Dec - 09 Jan	Qantas
27 Dec - 11 Jan	Qantas
24 Dec - 31 Dec	Qantas	direct
16 Dec - 28 Dec	Qantas
22 Dec - 29 Dec	Qantas	direct
21 Dec - 22 Dec	Qantas
16 Dec - 28 Dec	Qantas	direct

Also check the deals for one-way flights from Melbourne to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Melbourne to Santiago in December from $2165

Return flights