Cheapest one-way flights from Melbourne to Santiago in September from $1171

Best time to book flights for Melbourne (MEL) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Melbourne (MEL) to Santiago (SCL) in September 2025 (see full year).

One-Way flights

17 Sep Philippine Airlines
16 Sep LATAM Airlines Group
10 Sep LATAM Airlines Group direct
17 Sep LATAM Airlines Group direct
06 Sep LATAM Airlines Group direct
03 Sep LATAM Airlines Group direct
01 Sep LATAM Airlines Group direct
08 Sep LATAM Airlines Group direct
13 Sep LATAM Airlines Group direct
15 Sep LATAM Airlines Group direct

Also check the deals for return flights from Melbourne to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago