Cheapest one-way flights from Mexico City to Santiago in October from $207

Best time to book flights for Mexico City (MEX) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Mexico City (MEX) to Santiago (SCL) in October 2025 (see full year).

One-Way flights

05 Oct Arajet
02 Oct Arajet
25 Oct Avianca
24 Oct Arajet
03 Oct Avianca
01 Oct Volaris
06 Oct LATAM Airlines Group direct
01 Oct LATAM Airlines Group direct
24 Oct LATAM Airlines Group direct
02 Oct LATAM Airlines Group direct

Also check the deals for return flights from Mexico City to Santiago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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