AirHint found the following cheapest one-way flights from Porto (OPO) to Istanbul (IST) in May 2026 (see full year).

One-Way flights

20 May	Air Europa
13 May	Air Europa
19 May	Air Europa
04 May	Vueling Airlines
03 May	Ryanair
16 May	Vueling Airlines
21 May	Vueling Airlines
17 May	Vueling Airlines
01 May	Aegean Airlines
04 May	Turkish Airlines	direct

Also check the deals for return flights from Porto to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Porto to Istanbul in May from $76

One-Way flights