AirHint found the following cheapest return flights from Porto (OPO) to Istanbul (IST) in May 2026 (see full year).

Return flights

07 May - 08 May	easyJet
08 May - 11 May	easyJet
11 May - 16 May	easyJet
04 May - 11 May	easyJet
14 May - 24 May	easyJet
05 May - 06 May	easyJet
16 May - 24 May	easyJet
06 May - 10 May	easyJet
15 May - 24 May	easyJet
01 May - 07 May	easyJet
27 May - 02 Jun	Lufthansa
30 May - 13 Jun	easyJet
27 May - 16 Jun	Vueling Airlines
27 May - 17 Jun	Vueling Airlines
16 May - 01 Jun	Vueling Airlines
27 May - 01 Jun	Vueling Airlines
26 May - 16 Jun	Vueling Airlines
16 May - 03 Jun	Vueling Airlines
27 May - 12 Jun	Vueling Airlines
27 May - 03 Jun	Vueling Airlines

Also check the deals for one-way flights from Porto to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Porto to Istanbul in May from $227

Return flights