Cheapest one-way flights from Chicago to Rome in October from $222

Best time to book flights for Chicago (ORD) to Rome (FCO) flights at AirHint

AirHint found the following cheapest one-way flights from Chicago (ORD) to Rome (FCO) in October 2025 (see full year).

One-Way flights

17 Oct Spirit Airlines
22 Oct Spirit Airlines
19 Oct Spirit Airlines
24 Oct Spirit Airlines
04 Oct Spirit Airlines
08 Oct Spirit Airlines
10 Oct Icelandair
09 Oct Turkish Airlines
19 Oct United direct
24 Oct American Airlines direct

Also check the deals for return flights from Chicago to Rome in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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