AirHint found the following cheapest return flights from Chicago (ORD) to Rome (FCO) in October 2025 (see full year).

Return flights

29 Oct - 22 Nov	TAP
30 Oct - 06 Nov	Icelandair
29 Oct - 03 Nov	Austrian Airlines
11 Oct - 22 Oct	TAP
29 Oct - 05 Nov	SWISS
19 Oct - 08 Nov	TAP
14 Oct - 08 Nov	Air Canada
15 Oct - 08 Nov	Air Canada
16 Oct - 08 Nov	Icelandair
20 Oct - 24 Nov	Iberia
17 Oct - 08 Nov	Icelandair
15 Oct - 22 Oct	Lufthansa
16 Oct - 23 Oct	Iberia
21 Oct - 28 Oct	Turkish Airlines
23 Oct - 28 Oct	Turkish Airlines
16 Oct - 19 Oct	Icelandair
19 Oct - 23 Oct	TAP
08 Oct - 15 Oct	Spirit Airlines
18 Oct - 26 Oct	Turkish Airlines
12 Oct - 19 Oct	Icelandair

Also check the deals for one-way flights from Chicago to Rome in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Rome in October from $377

Return flights