Cheapest one-way flights from Chicago to Istanbul in May from $272

AirHint found the following cheapest one-way flights from Chicago (ORD) to Istanbul (IST) in May 2026 (see full year).

One-Way flights

04 May Icelandair
07 May Frontier Airlines
08 May Icelandair
03 May Icelandair
19 May Icelandair
16 May Spirit Airlines
15 May Spirit Airlines
30 May Icelandair
20 May Spirit Airlines
19 May Turkish Airlines direct

Also check the deals for return flights from Chicago to Istanbul in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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