AirHint found the following cheapest return flights from Chicago (ORD) to Istanbul (IST) in May 2026 (see full year).

Return flights

01 May - 08 May	Icelandair
06 May - 13 May	Icelandair
07 May - 17 May	Frontier Airlines
02 May - 16 May	Scandinavian Airlines
01 May - 13 May	Scandinavian Airlines
03 May - 12 May	Lufthansa
01 May - 25 May	Icelandair
15 May - 11 Jun	Icelandair
02 May - 13 May	Lufthansa
19 May - 26 May	Scandinavian Airlines
16 May - 26 May	Scandinavian Airlines
23 May - 07 Jun	Air Canada
22 May - 06 Jun	Icelandair
21 May - 05 Jun	Spirit Airlines
21 May - 03 Jun	Spirit Airlines
21 May - 01 Jun	KLM
21 May - 02 Jun	KLM
21 May - 04 Jun	KLM
26 May - 25 Jun	KLM
22 May - 05 Jun	Spirit Airlines

Also check the deals for one-way flights from Chicago to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul

Cheapest return flights from Chicago to Istanbul in May from $625

Return flights