Cheapest one-way flights from Santiago to Sao Paulo in December from $128

AirHint found the following cheapest one-way flights from Santiago (SCL) to Sao Paulo (GRU) in December 2025 (see full year).

One-Way flights

18 Dec Sky Airline direct
23 Dec Sky Airline direct
15 Dec LATAM Airlines Group
19 Dec LATAM Airlines Group
15 Dec Sky Airline direct
01 Dec Sky Airline direct
19 Dec Sky Airline direct
27 Dec LATAM Airlines Group direct
26 Dec Aerolineas Argentinas
30 Dec Aerolineas Argentinas

Also check the deals for return flights from Santiago to Sao Paulo in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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