Cheapest one-way flights from Santiago to Sao Paulo in December from $74

AirHint found the following cheapest one-way flights from Santiago (SCL) to Sao Paulo (GRU) in December 2025 (see full year).

One-Way flights

01 Dec Sky Airline direct
05 Dec Sky Airline direct
18 Dec Sky Airline direct
25 Dec Sky Airline direct
13 Dec Sky Airline direct
08 Dec Sky Airline direct
24 Dec Sky Airline direct
02 Dec Sky Airline direct
09 Dec Sky Airline direct
15 Dec Sky Airline direct

Also check the deals for return flights from Santiago to Sao Paulo in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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