AirHint found the following cheapest return flights from Santiago (SCL) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

06 Dec - 14 Dec	Sky Airline	direct
02 Dec - 08 Dec	LATAM Airlines Group
31 Dec - 04 Jan	LATAM Airlines Group
02 Dec - 08 Dec	Sky Airline	direct
30 Dec - 02 Jan	Sky Airline
28 Dec - 05 Jan	LATAM Airlines Group	direct
31 Dec - 04 Jan	Sky Airline	direct
30 Dec - 06 Jan	Sky Airline
30 Dec - 02 Jan	Sky Airline	direct
30 Dec - 06 Jan	Sky Airline	direct

Also check the deals for one-way flights from Santiago to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Sao Paulo in December from $231

Return flights