Cheapest one-way flights from Santiago to La Serena in October from $28

AirHint found the following cheapest one-way flights from Santiago (SCL) to La Serena (LSC) in October 2025 (see full year).

One-Way flights

23 Oct Sky Airline direct
20 Oct Sky Airline direct
17 Oct LATAM Airlines Group direct
06 Oct Sky Airline direct
08 Oct Sky Airline direct
09 Oct JetSmart direct
12 Oct JetSmart direct
24 Oct LATAM Airlines Group direct
30 Oct JetSmart direct

Also check the deals for return flights from Santiago to La Serena in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in La Serena

Cheap car rent in La Serena

Feel free to contact us with any feedback or request another flight research.