Cheapest one-way flights from Santiago to La Serena in October from $26

AirHint found the following cheapest one-way flights from Santiago (SCL) to La Serena (LSC) in October 2025 (see full year).

One-Way flights

09 Oct LATAM Airlines Group direct
08 Oct LATAM Airlines Group direct
11 Oct LATAM Airlines Group direct
13 Oct LATAM Airlines Group direct
04 Oct LATAM Airlines Group direct
01 Oct LATAM Airlines Group direct
07 Oct LATAM Airlines Group direct
21 Oct JetSmart direct
25 Oct JetSmart direct
29 Oct Sky Airline direct

Also check the deals for return flights from Santiago to La Serena in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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