Cheapest one-way flights from Santiago to La Serena in December from $30

AirHint found the following cheapest one-way flights from Santiago (SCL) to La Serena (LSC) in December 2025 (see full year).

One-Way flights

14 Dec JetSmart direct
19 Dec JetSmart direct
27 Dec Sky Airline direct
04 Dec JetSmart direct

Also check the deals for return flights from Santiago to La Serena in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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