Cheapest one-way flights from Santiago to Madrid in October from $392

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in October 2025 (see full year).

One-Way flights

23 Oct Sky Airline
16 Oct LATAM Airlines Group
26 Oct LATAM Airlines Group
12 Oct Sky Airline
22 Oct Aerolineas Argentinas
31 Oct Sky Airline
20 Oct Sky Airline
28 Oct Sky Airline
21 Oct Sky Airline
02 Oct Sky Airline

Also check the deals for return flights from Santiago to Madrid in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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