AirHint found the following cheapest return flights from Santiago (SCL) to Madrid (MAD) in October 2025 (see full year).

Return flights

26 Oct - 03 Nov	Sky Airline
22 Oct - 20 Nov	LATAM Airlines Group
29 Oct - 19 Nov	LATAM Airlines Group
17 Oct - 27 Nov	LATAM Airlines Group
29 Oct - 19 Nov	Iberia	direct
29 Oct - 22 Nov	LATAM Airlines Group	direct
28 Oct - 11 Nov	LATAM Airlines Group
26 Oct - 18 Nov	LATAM Airlines Group
31 Oct - 21 Nov	Iberia	direct
20 Oct - 14 Nov	Iberia	direct
10 Oct - 25 Oct	Avianca
07 Oct - 26 Oct	Avianca
12 Oct - 22 Oct	Avianca
05 Oct - 28 Oct	Avianca
07 Oct - 27 Oct	Avianca
09 Oct - 22 Oct	Avianca
07 Oct - 21 Oct	Avianca
10 Oct - 21 Oct	Avianca
13 Oct - 20 Oct	Avianca
14 Oct - 21 Oct	Avianca

Also check the deals for one-way flights from Santiago to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Madrid in October from $823

Return flights