Cheapest one-way flights from Santiago to Mexico City in December from $250

AirHint found the following cheapest one-way flights from Santiago (SCL) to Mexico City (MEX) in December 2025 (see full year).

One-Way flights

10 Dec Aeromexico direct
13 Dec LATAM Airlines Group direct
31 Dec Arajet
01 Dec Sky Airline
08 Dec Aeromexico direct
14 Dec LATAM Airlines Group direct
05 Dec Sky Airline
04 Dec Sky Airline
15 Dec Sky Airline
16 Dec Sky Airline

Also check the deals for return flights from Santiago to Mexico City in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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