Cheapest one-way flights from Santiago to Mexico City in December from $265

AirHint found the following cheapest one-way flights from Santiago (SCL) to Mexico City (MEX) in December 2025 (see full year).

One-Way flights

08 Dec Avianca
24 Dec LATAM Airlines Group
04 Dec JetSmart
05 Dec Sky Airline
09 Dec JetSmart
11 Dec LATAM Airlines Group
01 Dec Sky Airline
24 Dec Aeromexico direct
19 Dec LATAM Airlines Group direct
12 Dec LATAM Airlines Group

Also check the deals for return flights from Santiago to Mexico City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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