Cheapest return flights from Santiago to Mexico City in December from $541

AirHint found the following cheapest return flights from Santiago (SCL) to Mexico City (MEX) in December 2025 (see full year).

Return flights

10 Dec - 31 Dec LATAM Airlines Group
02 Dec - 16 Dec Copa
08 Dec - 15 Dec Copa
09 Dec - 24 Dec Copa
01 Dec - 10 Dec Copa
01 Dec - 13 Dec Copa
05 Dec - 15 Dec Copa
15 Dec - 12 Jan LATAM Airlines Group
04 Dec - 02 Jan LATAM Airlines Group
22 Dec - 05 Jan LATAM Airlines Group
02 Dec - 08 Dec Avianca
08 Dec - 15 Dec LATAM Airlines Group direct
15 Dec - 30 Dec LATAM Airlines Group
27 Dec - 13 Jan LATAM Airlines Group direct
25 Dec - 03 Jan LATAM Airlines Group direct
31 Dec - 15 Jan Copa
31 Dec - 15 Jan LATAM Airlines Group direct
15 Dec - 12 Jan LATAM Airlines Group direct
19 Dec - 03 Jan LATAM Airlines Group direct
19 Dec - 08 Jan LATAM Airlines Group direct

Also check the deals for one-way flights from Santiago to Mexico City in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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