Cheapest return flights from Santiago to Mexico City in December from $541
AirHint found the following cheapest return flights from Santiago (SCL) to Mexico City (MEX)
in December 2025 (see full year ).
Return flights
10 Dec
- 31 Dec
LATAM Airlines Group
$ 541
02 Dec
- 16 Dec
Copa
$ 546
08 Dec
- 15 Dec
Copa
$ 546
09 Dec
- 24 Dec
Copa
$ 546
01 Dec
- 10 Dec
Copa
$ 546
01 Dec
- 13 Dec
Copa
$ 560
05 Dec
- 15 Dec
Copa
$ 560
15 Dec
- 12 Jan
LATAM Airlines Group
$ 574
04 Dec
- 02 Jan
LATAM Airlines Group
$ 574
22 Dec
- 05 Jan
LATAM Airlines Group
$ 578
02 Dec
- 08 Dec
Avianca
$ 594
08 Dec
- 15 Dec
LATAM Airlines Group
$ 615
direct
15 Dec
- 30 Dec
LATAM Airlines Group
$ 615
27 Dec
- 13 Jan
LATAM Airlines Group
$ 616
direct
25 Dec
- 03 Jan
LATAM Airlines Group
$ 617
direct
31 Dec
- 15 Jan
Copa
$ 628
31 Dec
- 15 Jan
LATAM Airlines Group
$ 633
direct
15 Dec
- 12 Jan
LATAM Airlines Group
$ 637
direct
19 Dec
- 03 Jan
LATAM Airlines Group
$ 711
direct
19 Dec
- 08 Jan
LATAM Airlines Group
$ 717
direct
Also check the deals for one-way flights from Santiago to Mexico City in December .
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers.
Only the cheapest flights are offered.
Select a price to book and secure these cheap prices.
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