Cheapest one-way flights from Santiago to Prague in September from $67

AirHint found the following cheapest one-way flights from Santiago (SCQ) to Prague (PRG) in September 2025 (see full year).

One-Way flights

09 Sep Vueling Airlines
13 Sep Vueling Airlines
29 Sep Ryanair
12 Sep Vueling Airlines
11 Sep Ryanair
15 Sep Ryanair
10 Sep Vueling Airlines
18 Sep Vueling Airlines
30 Sep Ryanair
20 Sep Vueling Airlines

Also check the deals for return flights from Santiago to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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