Cheapest return flights from Santiago to Prague in September from $214

Best time to book flights for Santiago (SCQ) to Prague (PRG) flights at AirHint

AirHint found the following cheapest return flights from Santiago (SCQ) to Prague (PRG) in September 2025 (see full year).

Return flights

08 Sep - 11 Sep Vueling Airlines
18 Sep - 21 Sep Vueling Airlines
04 Sep - 08 Sep Iberia
08 Sep - 13 Sep Vueling Airlines
02 Sep - 05 Sep Iberia
01 Sep - 05 Sep Ryanair
04 Sep - 21 Sep Vueling Airlines
07 Sep - 12 Sep easyJet
11 Sep - 21 Sep Vueling Airlines
04 Sep - 07 Sep Iberia
23 Sep - 10 Oct Vueling Airlines

Also check the deals for one-way flights from Santiago to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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