Cheapest return flights from Santiago to Prague in September from $167

AirHint found the following cheapest return flights from Santiago (SCQ) to Prague (PRG) in September 2025 (see full year).

Return flights

24 Sep - 01 Oct Ryanair
23 Sep - 30 Sep Ryanair
18 Sep - 22 Sep Vueling Airlines
27 Sep - 29 Sep Ryanair
20 Sep - 23 Sep Ryanair
22 Sep - 26 Sep Ryanair
16 Sep - 20 Sep Ryanair
18 Sep - 23 Sep Ryanair
29 Sep - 06 Oct Ryanair
26 Sep - 28 Sep Ryanair
15 Sep - 18 Sep Vueling Airlines
15 Sep - 19 Sep Vueling Airlines

Also check the deals for one-way flights from Santiago to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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