Cheapest one-way flights from Santo Domingo to Madrid in September from 456€

AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

13 Sep Spirit Airlines
17 Sep Air Europa direct
20 Sep Air Europa direct
24 Sep Air Europa direct
28 Sep Air Europa direct
16 Sep Air Europa direct
27 Sep Air Europa direct
18 Sep Air Europa direct
29 Sep Air Europa direct
19 Sep Air Europa direct

Also check the deals for return flights from Santo Domingo to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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