Cheapest one-way flights from San Francisco to Guatemala City in December from $180

AirHint found the following cheapest one-way flights from San Francisco (SFO) to Guatemala City (GUA) in December 2025 (see full year).

One-Way flights

31 Dec Alaska Airlines
03 Dec United
04 Dec United
27 Dec American Airlines
10 Dec United
01 Dec Avianca
15 Dec Aeromexico
16 Dec Alaska Airlines
26 Dec United
20 Dec Frontier Airlines

Also check the deals for return flights from San Francisco to Guatemala City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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