AirHint found the following cheapest return flights from San Francisco (SFO) to Guatemala City (GUA) in December 2025 (see full year).

Return flights

03 Dec - 16 Dec	Frontier Airlines
03 Dec - 18 Dec	Frontier Airlines
04 Dec - 09 Dec	Frontier Airlines
03 Dec - 10 Dec	Frontier Airlines
08 Dec - 21 Dec	Frontier Airlines
14 Dec - 18 Dec	Frontier Airlines
12 Dec - 19 Dec	Frontier Airlines
28 Dec - 16 Jan	Frontier Airlines
13 Dec - 18 Dec	Frontier Airlines
14 Dec - 20 Dec	Frontier Airlines
12 Dec - 14 Dec	Frontier Airlines
21 Dec - 16 Jan	Frontier Airlines
17 Dec - 11 Jan	jetBlue
12 Dec - 02 Jan	Frontier Airlines
17 Dec - 04 Jan	jetBlue
22 Dec - 01 Jan	Frontier Airlines
31 Dec - 08 Jan	United
25 Dec - 02 Jan	Frontier Airlines
19 Dec - 03 Jan	jetBlue
24 Dec - 03 Jan	Avianca

Also check the deals for one-way flights from San Francisco to Guatemala City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Guatemala City in December from $338

Return flights