AirHint found the following cheapest return flights from San Francisco (SFO) to Guatemala City (GUA) in December 2025 (see full year).

Return flights

05 Dec - 09 Dec	Frontier Airlines
02 Dec - 09 Dec	Frontier Airlines
07 Dec - 21 Dec	Frontier Airlines
03 Dec - 10 Dec	Frontier Airlines
31 Dec - 08 Jan	Alaska Airlines
22 Dec - 06 Jan	Frontier Airlines
22 Dec - 31 Dec	Frontier Airlines
12 Dec - 05 Jan	Frontier Airlines
22 Dec - 01 Jan	Frontier Airlines
20 Dec - 29 Dec	Frontier Airlines
14 Dec - 05 Jan	Frontier Airlines
29 Dec - 05 Jan	Frontier Airlines
23 Dec - 04 Jan	Frontier Airlines
19 Dec - 11 Jan	Frontier Airlines
22 Dec - 26 Dec	United
26 Dec - 05 Jan	Frontier Airlines
17 Dec - 04 Jan	Hawaiian Airlines
12 Dec - 21 Dec	Avianca

Also check the deals for one-way flights from San Francisco to Guatemala City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Guatemala City in December from $354

Return flights