Cheapest one-way flights from Santa Cruz to Madrid in September from $594

Best time to book flights for Santa Cruz (VVI) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Santa Cruz (VVI) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

25 Sep Boliviana de Aviacion
20 Sep Boliviana de Aviacion
30 Sep GOL Linhas Aéreas
23 Sep GOL Linhas Aéreas
25 Sep Air Europa direct
19 Sep Avianca
21 Sep GOL Linhas Aéreas
13 Sep LATAM Airlines Group
15 Sep GOL Linhas Aéreas
18 Sep GOL Linhas Aéreas

Also check the deals for return flights from Santa Cruz to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid