Cheapest return flights from Santa Cruz to Madrid in September from $912

Best time to book flights for Santa Cruz (VVI) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest return flights from Santa Cruz (VVI) to Madrid (MAD) in September 2025 (see full year).

Return flights

25 Sep - 28 Sep Air Europa direct
25 Sep - 29 Sep Air Europa direct
15 Sep - 19 Sep Air Europa direct
26 Sep - 29 Sep Boliviana de Aviacion
30 Sep - 14 Oct GOL Linhas Aéreas
16 Sep - 31 Oct Iberia direct

Also check the deals for one-way flights from Santa Cruz to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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