AirHint found the following cheapest return flights from Cartagena (CTG) to Madrid (MAD) in December 2025 (see full year).

Return flights

03 Dec - 31 Jan	SWISS
24 Dec - 18 Jan	KLM
01 Dec - 30 Jan	KLM
10 Dec - 23 Dec	SWISS
29 Dec - 19 Jan	KLM
22 Dec - 17 Jan	KLM
22 Dec - 21 Jan	KLM
10 Dec - 27 Dec	SWISS
13 Dec - 30 Dec	KLM
20 Dec - 06 Jan	Avianca
14 Dec - 23 Dec	SWISS
21 Dec - 24 Jan	SWISS
01 Dec - 06 Jan	Avianca
22 Dec - 11 Jan	KLM
01 Dec - 29 Dec	Plus Ultra Lineas Aereas
01 Dec - 08 Dec	Plus Ultra Lineas Aereas
06 Dec - 27 Dec	KLM
13 Dec - 29 Dec	Plus Ultra Lineas Aereas
13 Dec - 27 Dec	Plus Ultra Lineas Aereas
06 Dec - 29 Dec	KLM

Also check the deals for one-way flights from Cartagena to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cartagena to Madrid in December from $724

Return flights