AirHint found the following cheapest return flights from Denver (DEN) to Rome (FCO) in September 2025 (see full year).

Return flights

05 Sep - 12 Sep	Icelandair
02 Sep - 12 Sep	Icelandair
03 Sep - 12 Sep	Frontier Airlines
21 Sep - 01 Oct	Frontier Airlines
22 Sep - 03 Oct	Aer Lingus
06 Sep - 20 Sep	Frontier Airlines
08 Sep - 15 Sep	Icelandair
01 Sep - 08 Sep	Air Canada
10 Sep - 15 Sep	Frontier Airlines
14 Sep - 20 Sep	Frontier Airlines
24 Sep - 06 Oct	Icelandair
10 Sep - 14 Sep	Frontier Airlines
29 Sep - 13 Oct	Aer Lingus
23 Sep - 03 Oct	jetBlue
26 Sep - 10 Oct	jetBlue
01 Sep - 16 Sep	Air Canada
29 Sep - 30 Oct	United
28 Sep - 31 Oct	Delta
30 Sep - 31 Oct	Delta
26 Sep - 03 Oct	United

Also check the deals for one-way flights from Denver to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Denver to Rome in September from $528

Return flights