Cheapest return flights from Guayaquil to Santiago in September from $387

AirHint found the following cheapest return flights from Guayaquil (GYE) to Santiago (SCL) in September 2025 (see full year).

Return flights

01 Sep - 06 Sep Avianca
10 Sep - 30 Sep Avianca
10 Sep - 26 Sep Avianca
15 Sep - 21 Oct Avianca
01 Sep - 30 Sep Avianca
15 Sep - 22 Oct Avianca
06 Sep - 20 Sep Avianca
10 Sep - 25 Sep Avianca
01 Sep - 05 Sep Avianca
15 Sep - 30 Sep Copa
05 Sep - 07 Sep Avianca
18 Sep - 22 Sep LATAM Airlines Group
08 Sep - 05 Oct Copa
14 Sep - 24 Oct Avianca
15 Sep - 28 Oct Copa
16 Sep - 22 Oct Avianca
15 Sep - 05 Oct Copa

Also check the deals for one-way flights from Guayaquil to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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